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Significance of Resveratrol in Clinical Management of Chronic Diseases.


ABSTRACT: Resveratrol could be beneficial to health and provides protection against a wide array of pathologies and age-associated problems, as evident from preclinical studies. However, a comparison of animal and human studies reveals that this dietary polyphenol cannot protect against metabolic diseases and their associated complications. The clinical outcomes are affected by many factors such as sample size. This article not only presents a comprehensive review of the current advances concerning the dose, the extent of absorption, interaction and toxicity of resveratrol in human studies, but also describes its therapeutic effects against several chronic diseases such as diabetes mellitus, obesity, cardiovascular diseases, cancer and aging and the related diseases.

SUBMITTER: Wahab A 

PROVIDER: S-EPMC6152193 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other

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Significance of Resveratrol in Clinical Management of Chronic Diseases.

Wahab Awais A   Gao Kuo K   Jia Caixia C   Zhang Feilong F   Tian Guihua G   Murtaza Ghulam G   Chen Jianxin J  

Molecules (Basel, Switzerland) 20170818 8


Resveratrol could be beneficial to health and provides protection against a wide array of pathologies and age-associated problems, as evident from preclinical studies. However, a comparison of animal and human studies reveals that this dietary polyphenol cannot protect against metabolic diseases and their associated complications. The clinical outcomes are affected by many factors such as sample size. This article not only presents a comprehensive review of the current advances concerning the do  ...[more]

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