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Chemotherapy-related Cardiomyopathy.


ABSTRACT: Advances in chemotherapeutic agents have resulted in significantly improved cancer survival rates. Cardiac toxicity, however, has emerged as a leading cause of morbidity, both during and years after treatment. One of the most common manifestations of cardiotoxicity is that of heart failure and left ventricular systolic dysfunction. In this review, current opinions and guidelines in this field are discussed, with particular focus on the most common culprits, the anthracyclines, and the monoclonal antibody, trastuzumab.

SUBMITTER: Piper SE 

PROVIDER: S-EPMC6159418 | biostudies-other | 2015 Jul

REPOSITORIES: biostudies-other

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Chemotherapy-related Cardiomyopathy.

Piper Susan E SE   McDonagh Theresa A TA  

European cardiology 20150701 1


Advances in chemotherapeutic agents have resulted in significantly improved cancer survival rates. Cardiac toxicity, however, has emerged as a leading cause of morbidity, both during and years after treatment. One of the most common manifestations of cardiotoxicity is that of heart failure and left ventricular systolic dysfunction. In this review, current opinions and guidelines in this field are discussed, with particular focus on the most common culprits, the anthracyclines, and the monoclonal  ...[more]

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