Ontology highlight
ABSTRACT:
SUBMITTER: Hanna GJ
PROVIDER: S-EPMC6171803 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Hanna Glenn J GJ Kacew Alec A Chau Nicole G NG Shivdasani Priyanka P Lorch Jochen H JH Uppaluri Ravindra R Haddad Robert I RI MacConaill Laura E LE
JCI insight 20180906 17
While it has been recognized that human papillomavirus-associated (HPV-associated) oropharyngeal cancer (OPC) portends an improved prognosis, distinct patterns of disease recurrence have emerged. Molecular characterization of this subset of HPV patients remains unexplored. We evaluated 52 metastatic HPV+ OPC patients from our institution and paired massively parallel sequencing data with clinical parameters and survival outcomes in 81% of patients. Genomic data were then compared with 2 molecula ...[more]