Dataset Information

Registration-Based Organ Positioning and Joint Segmentation Method for Liver and Tumor Segmentation.

ABSTRACT: The automated segmentation of liver and tumor from CT images is of great importance in medical diagnoses and clinical treatment. However, accurate and automatic segmentation of liver and tumor is generally complicated due to the complex anatomical structures and low contrast. This paper proposes a registration-based organ positioning (ROP) and joint segmentation method for liver and tumor segmentation from CT images. First, a ROP method is developed to obtain liver's bounding box accurately and efficiently. Second, a joint segmentation method based on fuzzy c-means (FCM) and extreme learning machine (ELM) is designed to perform coarse liver segmentation. Third, the coarse segmentation is regarded as the initial contour of active contour model (ACM) to refine liver boundary by considering the topological information. Finally, tumor segmentation is performed using another ELM. Experiments on two datasets demonstrate the performance advantages of our proposed method compared with other related works.

SUBMITTER: Jiang H

PROVIDER: S-EPMC6174803 | biostudies-other | 2018

REPOSITORIES: biostudies-other

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Registration-Based Organ Positioning and Joint Segmentation Method for Liver and Tumor Segmentation.

Jiang Huiyan H Li Shaojie S Li Siqi S

BioMed research international 20180924

The automated segmentation of liver and tumor from CT images is of great importance in medical diagnoses and clinical treatment. However, accurate and automatic segmentation of liver and tumor is generally complicated due to the complex anatomical structures and low contrast. This paper proposes a registration-based organ positioning (ROP) and joint segmentation method for liver and tumor segmentation from CT images. First, a ROP method is developed to obtain liver's bounding box accurately and ...[more]

PMID: 30345308

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Project description:PurposeAccurate segmentation of liver and liver tumors is critical for radiotherapy. Liver tumor segmentation, however, remains a difficult and relevant problem in the field of medical image processing because of the various factors like complex and variable location, size, and shape of liver tumors, low contrast between tumors and normal tissues, and blurred or difficult-to-define lesion boundaries. In this paper, we proposed a neural network (S-Net) that can incorporate attention mechanisms to end-to-end segmentation of liver tumors from CT images.MethodsFirst, this study adopted a classical coding-decoding structure to realize end-to-end segmentation. Next, we introduced an attention mechanism between the contraction path and the expansion path so that the network could encode a longer range of semantic information in the local features and find the corresponding relationship between different channels. Then, we introduced long-hop connections between the layers of the contraction path and the expansion path, so that the semantic information extracted in both paths could be fused. Finally, the application of closed operation was used to dissipate the narrow interruptions and long, thin divide. This eliminated small cavities and produced a noise reduction effect.ResultsIn this paper, we used the MICCAI 2017 liver tumor segmentation (LiTS) challenge dataset, 3DIRCADb dataset and doctors' manual contours of Hubei Cancer Hospital dataset to test the network architecture. We calculated the Dice Global (DG) score, Dice per Case (DC) score, volumetric overlap error (VOE), average symmetric surface distance (ASSD), and root mean square error (RMSE) to evaluate the accuracy of the architecture for liver tumor segmentation. The segmentation DG for tumor was found to be 0.7555, DC was 0.613, VOE was 0.413, ASSD was 1.186 and RMSE was 1.804. For a small tumor, DG was 0.3246 and DC was 0.3082. For a large tumor, DG was 0.7819 and DC was 0.7632.ConclusionS-Net obtained more semantic information with the introduction of an attention mechanism and long jump connection. Experimental results showed that this method effectively improved the effect of tumor recognition in CT images and could be applied to assist doctors in clinical treatment.

Dataset Information

Registration-Based Organ Positioning and Joint Segmentation Method for Liver and Tumor Segmentation.

Publications

Registration-Based Organ Positioning and Joint Segmentation Method for Liver and Tumor Segmentation.

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