Ontology highlight
ABSTRACT:
SUBMITTER: Kovarova M
PROVIDER: S-EPMC6175887 | biostudies-other | 2018 Oct
REPOSITORIES: biostudies-other
Nature communications 20181008 1
Non-adherence to medication is an important health care problem, especially in the treatment of chronic conditions. Injectable long-acting (LA) formulations of antiretrovirals (ARVs) represent a viable alternative to improve adherence to HIV/AIDS treatment and prevention. However, the LA-ARV formulations currently in clinical trials cannot be removed after administration even if adverse events occur. Here we show an ultra-LA removable system that delivers drug for up to 9 months and can be safel ...[more]