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Calcium Pyrophosphate Dihydrate Deposition Disease in Young Patients: Two Case Reports.

ABSTRACT: Calcium pyrophosphate deposition disease (CPDD) is a type of arthritis caused by the deposition of calcium pyrophosphate crystals, and may present as either acute or chronic arthritis. Development of CPPD crystal deposition disease in young people may be associated with metabolic diseases such as hemochromatosis, hyperparathyroidism, hypomagnesemia, Wilson's disease, hypothyroidism, gout, acromegaly, and X-linked hypophosphatemic rickets. Therefore, investigations for a predisposing metabolic condition are advised in young-onset polyarticular CPPD crystal deposition disease. In this article, we report two young patients who were investigated for recurrent joint pain due to CPPD disease.

SUBMITTER: Wickrematilake GW

PROVIDER: S-EPMC6190932 | biostudies-other | 2017 Mar

REPOSITORIES: biostudies-other

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Calcium Pyrophosphate Dihydrate Deposition Disease in Young Patients: Two Case Reports.

Wickrematilake Geetha Wickrematilake GW

Archives of rheumatology 20161208 1

Calcium pyrophosphate deposition disease (CPDD) is a type of arthritis caused by the deposition of calcium pyrophosphate crystals, and may present as either acute or chronic arthritis. Development of CPPD crystal deposition disease in young people may be associated with metabolic diseases such as hemochromatosis, hyperparathyroidism, hypomagnesemia, Wilson's disease, hypothyroidism, gout, acromegaly, and X-linked hypophosphatemic rickets. Therefore, investigations for a predisposing metabolic co ...[more]

PMID: 30375521

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The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.

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Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition disease.

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