Ontology highlight
ABSTRACT:
SUBMITTER: Dziegala M
PROVIDER: S-EPMC6204587 | biostudies-other | 2018 Oct
REPOSITORIES: biostudies-other
Journal of cachexia, sarcopenia and muscle 20180904 5
Specific skeletal myopathy constitutes a common feature of heart failure, chronic obstructive pulmonary disease, and type 2 diabetes mellitus, where it can be characterized by the loss of skeletal muscle oxidative capacity. There is evidence from in vitro and animal studies that iron deficiency affects skeletal muscle functioning mainly in the context of its energetics by limiting oxidative metabolism in favour of glycolysis and by alterations in both carbohydrate and fat catabolic processing. I ...[more]