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[11C]acetate PET as a tool for diagnosis of liver steatosis.


ABSTRACT: PURPOSE:To investigate [11C]acetate PET-surrogate parameter of fatty acid synthase activity-as suitable tool for diagnosis and monitoring of liver steatosis. METHODS:In this retrospective study, data were obtained from 83 prostatic carcinoma patients from 1/2008 to 1/2014. Mean HU was calculated from unenhanced CT of all patients from liver with liver HU less than 40 as threshold for liver steatosis. SUVmax of the liver and of the blood pool in thoracic aorta (as background for calculation of a liver/background ratio [SUVl/b]) was measured. t test was used with a P?

SUBMITTER: Nejabat M 

PROVIDER: S-EPMC6208816 | biostudies-other | 2018 Nov

REPOSITORIES: biostudies-other

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<h4>Purpose</h4>To investigate [<sup>11</sup>C]acetate PET-surrogate parameter of fatty acid synthase activity-as suitable tool for diagnosis and monitoring of liver steatosis.<h4>Methods</h4>In this retrospective study, data were obtained from 83 prostatic carcinoma patients from 1/2008 to 1/2014. Mean HU was calculated from unenhanced CT of all patients from liver with liver HU less than 40 as threshold for liver steatosis. SUV<sub>max</sub> of the liver and of the blood pool in thoracic aorta  ...[more]

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