Ontology highlight
ABSTRACT:
SUBMITTER: Kawashima S
PROVIDER: S-EPMC6212420 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Kawashima Saki S Funakoshi Tomoko T Sato Yasunori Y Saito Norikatsu N Ohsawa Hajime H Kurita Katsumi K Nagata Kisaburo K Yoshida Masayuki M Ishigami Akihito A
Scientific reports 20181101 1
Several studies have reported the effects of vitamin C (L-ascorbic acid, AA) on ultraviolet B (UVB)-induced cell damage using cultured keratinocytes. However, the epidermis consists of multiple cell layers, and the effect of AA on UVB-induced damage to the human epidermis remains unclear. Therefore, we investigated the effect of AA on UVB-induced skin damage using reconstituted human epidermis. The reconstituted human epidermal surface was treated with 100 and 500 mM AA and cultured for 3 h befo ...[more]