Evolving Pharmacotherapeutic Strategies for Type 1 Diabetes Mellitus.

ABSTRACT: Despite pharmacotherapeutic advancements in the management of type 1 diabetes mellitus during the past several decades, patients struggle to achieve glycemic goals. Additionally, hypoglycemia, especially in extremes of age, decreases quality of life. The lack of optimal glycemic control and risk for hypoglycemia are multifactorial. Nevertheless, endeavors aiming to develop pharmacotherapeutic options with enhanced pharmacokinetic, pharmacodynamic, and clinical profiles continue. This review article discusses recent ventures in 3 categories of insulin, non-insulin, and glucagon products.

SUBMITTER: Sabet S 

PROVIDER: S-EPMC6213629 | biostudies-other | 2018 Sep-Oct

REPOSITORIES: biostudies-other