Ontology highlight
ABSTRACT:
SUBMITTER: Luo M
PROVIDER: S-EPMC6223079 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Luo Mengdie M Zhang Ziyu Z Peng Yani Y Wang Shuai S Peng Daoquan D
Cardiovascular diabetology 20181108 1
<h4>Background</h4>It is well known that angiopoietin-like protein 8 (ANGPTL8) exerts its effects on lipid metabolism through the inhibition of lipoprotein lipase and subsequent elevation of plasma triglyceride. However, it is not clear whether ANGPTL8 could affect lipid metabolism via other pathways. The study was aimed to investigate the effects of ANGPTL8 on the function of high-density lipoprotein (HDL), which plays a protective role in atherosclerosis progression.<h4>Methods</h4>Two hundred ...[more]