Unknown

Dataset Information

0

The impact of maternal gestational weight gain on cardiometabolic risk factors in children.


ABSTRACT: AIMS/HYPOTHESIS:Accumulating evidence suggests an impact of gestational weight gain (GWG) on pregnancy outcomes; however, data on cardiometabolic risk factors later in life have not been comprehensively studied. This study aimed to evaluate the relationship between GWG and cardiometabolic risk in offspring aged 7 years. METHODS:We included a total of 905 mother-child pairs who enrolled in the follow-up visit of the multicentre Hyperglycemia and Adverse Pregnancy Outcome study, at the Hong Kong Centre. Women were classified as having gained weight below, within or exceeding the 2009 Institute of Medicine (IOM) guidelines. A standardised GWG according to pre-pregnancy BMI categories was calculated to explore for any quadratic relationship. RESULTS:Independent of pre-pregnancy BMI, gestational hyperglycaemia and other confounders, women who gained more weight than the IOM recommendations had offspring with a larger body size and increased odds of adiposity, hypertension and insulin resistance (range of p values of all the traits: 4.6?×?10-9?

SUBMITTER: Tam CHT 

PROVIDER: S-EPMC6223878 | biostudies-other | 2018 Dec

REPOSITORIES: biostudies-other

altmetric image

Publications

The impact of maternal gestational weight gain on cardiometabolic risk factors in children.

Tam Claudia H T CHT   Ma Ronald C W RCW   Yuen Lai Yuk LY   Ozaki Risa R   Li Albert Martin AM   Hou Yong Y   Chan Michael H M MHM   Ho Chung Shun CS   Yang Xilin X   Chan Juliana C N JCN   Tam Wing Hung WH  

Diabetologia 20180917 12


<h4>Aims/hypothesis</h4>Accumulating evidence suggests an impact of gestational weight gain (GWG) on pregnancy outcomes; however, data on cardiometabolic risk factors later in life have not been comprehensively studied. This study aimed to evaluate the relationship between GWG and cardiometabolic risk in offspring aged 7 years.<h4>Methods</h4>We included a total of 905 mother-child pairs who enrolled in the follow-up visit of the multicentre Hyperglycemia and Adverse Pregnancy Outcome study, at  ...[more]

Similar Datasets

| S-EPMC4731302 | biostudies-literature
| S-EPMC5490606 | biostudies-literature
| S-EPMC4187236 | biostudies-literature
| S-EPMC4827014 | biostudies-other
| S-EPMC6997086 | biostudies-literature
| S-EPMC5066566 | biostudies-literature
| S-EPMC5784805 | biostudies-literature
| S-EPMC4065732 | biostudies-literature
| S-EPMC4958727 | biostudies-literature
| S-EPMC5794623 | biostudies-other