Tauopathy and neurodegeneration: A role for stress.
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ABSTRACT:
SUBMITTER: Sierra-Fonseca JA
PROVIDER: S-EPMC6234266 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Publications
Tauopathy and neurodegeneration: A role for stress.
Sierra-Fonseca Jorge A JA Gosselink Kristin L KL
Neurobiology of stress 20180901
Neurodegenerative diseases are characterized by an irreversible and progressive loss of neuronal structure and function. While many alterations to normal cellular processes occur during neurodegeneration, a pathological accumulation of aggregated proteins constitutes a hallmark of several neurodegenerative disorders. Alzheimer's disease, specifically, is pathologically defined by the formation of amyloid plaques and tangles of hyperphosphorylated tau protein. Stress has emerged as an important f ...[more]
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