Chronic pulmonary exposure to traffic-related fine particulate matter causes brain impairment in adult rats.
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ABSTRACT:
SUBMITTER: Shih CH
PROVIDER: S-EPMC6234801 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Publications
Chronic pulmonary exposure to traffic-related fine particulate matter causes brain impairment in adult rats.
Shih Chi-Hsiang CH Chen Jen-Kun JK Kuo Li-Wei LW Cho Kuan-Hung KH Hsiao Ta-Chih TC Lin Zhe-Wei ZW Lin Yi-Syuan YS Kang Jiunn-Horng JH Lo Yu-Chun YC Chuang Kai-Jen KJ Cheng Tsun-Jen TJ Chuang Hsiao-Chi HC
Particle and fibre toxicology 20181109 1
<h4>Background</h4>Effects of air pollution on neurotoxicity and behavioral alterations have been reported. The objective of this study was to investigate the pathophysiology caused by particulate matter (PM) in the brain. We examined the effects of traffic-related particulate matter with an aerodynamic diameter of < 1 μm (PM<sub>1</sub>), high-efficiency particulate air (HEPA)-filtered air, and clean air on the brain structure, behavioral changes, brainwaves, and bioreactivity of the brain (cor ...[more]
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