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Amplification of Mitochondrial Activity in the Healing Response Following Rotator Cuff Tendon Injury.

ABSTRACT: Mitochondrial function following rotator cuff tendon injury (RCI) influences the tendon healing. We examined the mitochondrial morphology and function under hypoxia in the shoulder tendon tissue from surgically-induced tenotomy-RCI rat model and cultured swine tenocytes. The tendon tissue was collected post-injury on 3-5 (Group-A), 10-12 (Group-B), and 22-24 (Group-C), days and the corresponding contralateral tendons were used as control for each group. There was higher protein expression of citrate synthase (P?

SUBMITTER: Thankam FG 

PROVIDER: S-EPMC6242817 | biostudies-other | 2018 Nov

REPOSITORIES: biostudies-other

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Amplification of Mitochondrial Activity in the Healing Response Following Rotator Cuff Tendon Injury.

Thankam Finosh G FG   Chandra Isaiah S IS   Kovilam Anuradha N AN   Diaz Connor G CG   Volberding Benjamin T BT   Dilisio Matthew F MF   Radwan Mohamed M MM   Gross R Michael RM   Agrawal Devendra K DK  

Scientific reports 20181119 1

Mitochondrial function following rotator cuff tendon injury (RCI) influences the tendon healing. We examined the mitochondrial morphology and function under hypoxia in the shoulder tendon tissue from surgically-induced tenotomy-RCI rat model and cultured swine tenocytes. The tendon tissue was collected post-injury on 3-5 (Group-A), 10-12 (Group-B), and 22-24 (Group-C), days and the corresponding contralateral tendons were used as control for each group. There was higher protein expression of cit  ...[more]