Ontology highlight
ABSTRACT:
SUBMITTER: Cara FD
PROVIDER: S-EPMC6249834 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Di Cara Francesca F Bülow Margret H MH Simmonds Andrew J AJ Rachubinski Richard A RA
Molecular biology of the cell 20180906 22
The gut has a central role in digestion and nutrient absorption, but it also serves in defending against pathogens, engages in mutually beneficial interactions with commensals, and is a major source of endocrine signals. Gut homeostasis is necessary for organismal health and changes to the gut are associated with conditions like obesity and diabetes and inflammatory illnesses like Crohn's disease. We report that peroxisomes, organelles involved in lipid metabolism and redox balance, are required ...[more]