Ontology highlight
ABSTRACT:
SUBMITTER: Vorselen D
PROVIDER: S-EPMC6251882 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Vorselen Daan D van Dommelen Susan M SM Sorkin Raya R Piontek Melissa C MC Schiller Jürgen J Döpp Sander T ST Kooijmans Sander A A SAA van Oirschot Brigitte A BA Versluijs Birgitta A BA Bierings Marc B MB van Wijk Richard R Schiffelers Raymond M RM Wuite Gijs J L GJL Roos Wouter H WH
Nature communications 20181123 1
Extracellular vesicles (EVs) are widely studied regarding their role in cell-to-cell communication and disease, as well as for applications as biomarkers or drug delivery vehicles. EVs contain membrane and intraluminal proteins, affecting their structure and thereby likely their functioning. Here, we use atomic force microscopy for mechanical characterization of erythrocyte, or red blood cell (RBC), EVs from healthy individuals and from patients with hereditary spherocytosis (HS) due to ankyrin ...[more]