The utility of urinary CD80 as a diagnostic marker in patients with renal diseases.
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ABSTRACT:
SUBMITTER: Minamikawa S
PROVIDER: S-EPMC6251900 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Publications
The utility of urinary CD80 as a diagnostic marker in patients with renal diseases.
Minamikawa Shogo S Nozu Kandai K Maeta Shingo S Yamamura Tomohiko T Nakanishi Keita K Fujimura Junya J Horinouchi Tomoko T Nagano China C Sakakibara Nana N Nagase Hiroaki H Shima Hideaki H Noda Kenta K Ninchoji Takeshi T Kaito Hiroshi H Iijima Kazumoto K
Scientific reports 20181123 1
CD80, which regulates T cell activation, may provide a differential diagnostic marker between minimal change disease (MCD) and other renal diseases, including focal segmental glomerular sclerosis (FSGS). However, recent reports show contrasting results. Therefore, we evaluated the utility of urinary CD80 as a diagnostic biomarker. We collected 65 urine samples from 55 patients with MCD (n = 31), FSGS (n = 4), inherited nephrotic syndrome (n = 4), Alport syndrome (n = 5) and other glomerular dise ...[more]
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