Ontology highlight
ABSTRACT:
SUBMITTER: Vilaseca M
PROVIDER: S-EPMC6256317 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Vilaseca Marina M Guixé-Muntet Sergi S Fernández-Iglesias Anabel A Gracia-Sancho Jordi J
Therapeutic advances in gastroenterology 20181125
Portal hypertension represents one of the major clinical consequences of chronic liver disease, having a deep impact on patients' prognosis and survival. Its pathophysiology defines a pathological increase in the intrahepatic vascular resistance as the primary factor in its development, being subsequently aggravated by a paradoxical increase in portal blood inflow. Although extensive preclinical and clinical research in the field has been developed in recent decades, no effective treatment targe ...[more]