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Identifying Novel Signaling Pathways: An Exercise Scientists Guide to Phosphoproteomics.


ABSTRACT: We propose that phosphoproteomic-based studies will radically advance our knowledge about exercise-regulated signaling events. However, these studies use cutting-edge technologies that can be difficult for nonspecialists to understand. Hence, this review is intended to help nonspecialists 1) understand the fundamental technologies behind phosphoproteomic analysis and 2) use various bioinformatic tools that can be used to interrogate phosphoproteomic datasets.

SUBMITTER: Wilson GM 

PROVIDER: S-EPMC6261359 | biostudies-other | 2018 Apr

REPOSITORIES: biostudies-other

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Identifying Novel Signaling Pathways: An Exercise Scientists Guide to Phosphoproteomics.

Wilson Gary M GM   Blanco Rocky R   Coon Joshua J JJ   Hornberger Troy A TA  

Exercise and sport sciences reviews 20180401 2


We propose that phosphoproteomic-based studies will radically advance our knowledge about exercise-regulated signaling events. However, these studies use cutting-edge technologies that can be difficult for nonspecialists to understand. Hence, this review is intended to help nonspecialists 1) understand the fundamental technologies behind phosphoproteomic analysis and 2) use various bioinformatic tools that can be used to interrogate phosphoproteomic datasets. ...[more]

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