Glycosyl-Nucleolipids as new bioinspired amphiphiles.
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ABSTRACT:
SUBMITTER: Latxague L
PROVIDER: S-EPMC6270249 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Publications
Glycosyl-Nucleolipids as new bioinspired amphiphiles.
Latxague Laurent L Patwa Amit A Amigues Eric E Barthélémy Philippe P
Molecules (Basel, Switzerland) 20130930 10
Four new Glycosyl-NucleoLipid (GNL) analogs featuring either a single fluorocarbon or double hydrocarbon chains were synthesized in good yields from azido thymidine as starting material. Physicochemical studies (surface tension measurements, differential scanning calorimetry) indicate that hydroxybutanamide-based GNLs feature endothermic phase transition temperatures like the previously reported double chain glycerol-based GNLs. The second generation of GNFs featuring a free nucleobase reported ...[more]
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