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A new hydroxychavicol dimer from the roots of Piper betle.

ABSTRACT: A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

SUBMITTER: Lin CF

PROVIDER: S-EPMC6270560 | biostudies-other | 2013

REPOSITORIES: biostudies-other

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A new hydroxychavicol dimer from the roots of Piper betle.

Lin Chwan-Fwu CF Hwang Tsong-Long TL Chien Chun-Chien CC Tu Huei-Yu HY Lay Horng-Liang HL

Molecules (Basel, Switzerland) 20130226 3

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils. ...[more]

PMID: 23442932

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