Ontology highlight
ABSTRACT:
SUBMITTER: Bourjot M
PROVIDER: S-EPMC6270878 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Molecules (Basel, Switzerland) 20140324 3
Trigocherrierin A (1) and trigocherriolide E (2), two new daphnane diterpenoid orthoesters (DDOs), and six chlorinated analogues, trigocherrins A, B, F and trigocherriolides A-C, were isolated from the leaves of Trigonostemon cherrieri. Their structures were identified by mass spectrometry, extensive one- and two-dimensional NMR spectroscopy and through comparison with data reported in the literature. These compounds are potent and selective inhibitors of chikungunya virus (CHIKV) replication. A ...[more]