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Trithiocyanurate complexes of iron, manganese and nickel and their anticholinesterase activity.

ABSTRACT: The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH3) were prepared and characterized by elemental analysis and spectroscopies. Crystal and molecular structures of the iron complex of composition [Fe(L1)](ttcH2)(ClO4)·EtOH·H2O (1), where L1 is Schiff base derived from tris(2-aminoethyl)amine and 2-pyridinecarboxaldehyde, were solved. It was found that the Schiff base is coordinated to the central iron atom by six nitrogens forming deformed octahedral arrangement, whereas trithiocyanurate(1-) anion, perchlorate and solvent molecules are not coordinated. The X-ray structure of the Schiff base sodium salt is also presented and compared with the iron complex. The anticholinesterase activity of the complexes was also studied.

SUBMITTER: Kopel P

PROVIDER: S-EPMC6272027 | biostudies-other | 2014 Apr

REPOSITORIES: biostudies-other

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Trithiocyanurate complexes of iron, manganese and nickel and their anticholinesterase activity.

Kopel Pavel P Dolezal Karel K Langer Vratislav V Jun Daniel D Adam Vojtech V Kuca Kamil K Kizek Rene R

Molecules (Basel, Switzerland) 20140408 4

The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH3) were prepared and characterized by elemental analysis and spectroscopies. Crystal and molecular structures of the iron complex of composition [Fe(L1)](ttcH2)(ClO4)·EtOH·H2O (1), where L1 is Schiff base derived from tris(2-aminoethyl)amine and 2-pyridinecarboxaldehyde, were solved. It was found that the Schiff base is coordinated to the centr ...[more]

PMID: 24717551

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