Ontology highlight
ABSTRACT:
SUBMITTER: Chen T
PROVIDER: S-EPMC6272659 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Chen Tingbo T Xiang Zheng Z Dong Gengting G Luo Pei P Qiu Ping P Wang Shenzhi S Huang Baoming B Wen Yingyi Y Wu Feichi F Liu Liang L Zhou Hua H
Molecules (Basel, Switzerland) 20150410 4
A sensitive, precise and selective ultra-high performance liquid chromatography method coupled with triple-quadrupole mass spectrometry was developed and validated for the determination of trace amounts of sinomenine (ng/mL) in minute volumes of human plasma. Fifty microliter plasma samples were precipitated using methanol to extract sinomenine. Separation was carried out on a C18 column with a water and acetonitrile mobile phase gradient with formic acid as an additive. The mass spectrometry da ...[more]