Ontology highlight
ABSTRACT:
SUBMITTER: Dahlmann HA
PROVIDER: S-EPMC6272844 | biostudies-other | 2016 May
REPOSITORIES: biostudies-other
Dahlmann Heidi A HA McKinney Amanda J AJ Santos Maria P MP Davis Lindsey O LO
Molecules (Basel, Switzerland) 20160531 6
An organocatalyzed intramolecular carbonyl-ene reaction was developed to produce carbocyclic and heterocyclic 5- and 6-membered rings from a citronellal-derived trifluoroketone and a variety of aldehydes. A phosphoramide derivative was found to promote the cyclization of the trifluoroketone, whereas a less acidic phosphoric acid proved to be a superior catalyst for the aldehyde substrates. ...[more]