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Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives.

ABSTRACT: Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented.

SUBMITTER: Zhang SG

PROVIDER: S-EPMC6278422 | biostudies-other | 2018 Oct

REPOSITORIES: biostudies-other

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Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives.

Zhang Shu-Guang SG Liang Chao-Gen CG Zhang Wei-Hua WH

Molecules (Basel, Switzerland) 20181026 11

Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compound ...[more]

PMID: 30373212

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