Ontology highlight
ABSTRACT:
SUBMITTER: Roscetto E
PROVIDER: S-EPMC6279838 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Roscetto Emanuela E Contursi Patrizia P Vollaro Adriana A Fusco Salvatore S Notomista Eugenio E Catania Maria Rosaria MR
Scientific reports 20181204 1
Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. The emergence of resistance to the most common antifungal drugs, also due to biofilm formation, requires the development of alternative antifungal agents. The antimicrobial peptide VLL-28, isolated from an archaeal transcription factor, shows comparable antifungal activity against 10 clinical isolates of Candida spp. Using a fluoresceinated derivative of this peptide, we ...[more]