Ontology highlight
ABSTRACT:
SUBMITTER: Lynch RM
PROVIDER: S-EPMC6284544 | biostudies-other | 2019 Jan
REPOSITORIES: biostudies-other
Lynch Rebecca M RM Mantus Grace G Encinales Liliana L Pacheco Nelly N Li Guangzhao G Porras Alexandra A Mendoza Alejandro R AR Peng Jin J Rengifo-Pardo Monica M Cruz Magelda Montoya MM Harris Eva E Bethony Jeff M JM Simon Gary L GL Chang Aileen Y AY
The Journal of infectious diseases 20190101 1
The role of neutralizing antibodies in Zika-induced Guillain-Barré syndrome (GBS) has not yet been investigated. We conducted a case-control study using sera from the 2016 Zika epidemic in Colombia to determine the neutralizing antibody activity against Zika virus (ZIKV) and dengue virus serotype 2 (DENV2). We observed increased neutralizing antibody titers against DENV2 in ZIKV-infected individuals compared with uninfected controls and higher titers to both ZIKV and DENV2 in ZIKV-infected patie ...[more]