Exosomes-the enigmatic regulators of bone homeostasis.
Ontology highlight
ABSTRACT:
SUBMITTER: Gao M
PROVIDER: S-EPMC6286319 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
Exosomes-the enigmatic regulators of bone homeostasis.
Gao Minhao M Gao Weiyang W Papadimitriou J M JM Zhang Changqing C Gao Junjie J Zheng Minghao M
Bone research 20181207
Exosomes are a heterogeneous group of cell-derived membranous structures, which mediate crosstalk interaction between cells. Recent studies have revealed a close relationship between exosomes and bone homeostasis. It is suggested that bone cells can spontaneously secret exosomes containing proteins, lipids and nucleic acids, which then to regulate osteoclastogenesis and osteogenesis. However, the network of regulatory activities of exosomes in bone homeostasis as well as their therapeutic potent ...[more]
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