Ontology highlight
ABSTRACT:
SUBMITTER: Truxova I
PROVIDER: S-EPMC6288908 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Truxova Iva I Kasikova Lenka L Hensler Michal M Skapa Petr P Laco Jan J Pecen Ladislav L Belicova Lucie L Praznovec Ivan I Halaska Michael J MJ Brtnicky Tomas T Salkova Eva E Rob Lukas L Kodet Roman R Goc Jeremy J Sautes-Fridman Catherine C Fridman Wolf Herman WH Ryska Ales A Galluzzi Lorenzo L Spisek Radek R Fucikova Jitka J
Journal for immunotherapy of cancer 20181204 1
A high density of tumor-infiltrating CD8<sup>+</sup> T cells and CD20<sup>+</sup> B cells correlates with prolonged survival in patients with a wide variety of human cancers, including high-grade serous ovarian carcinoma (HGSC). However, the potential impact of mature dendritic cells (DCs) in shaping the immune contexture of HGSC, their role in the establishment of T cell-dependent antitumor immunity, and their potential prognostic value for HGSC patients remain unclear. We harnessed immunohisto ...[more]