Ontology highlight
ABSTRACT:
SUBMITTER: Neokosmidis G
PROVIDER: S-EPMC6319130 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Neokosmidis Georgios G Tziomalos Konstantinos K
World journal of gastroenterology 20181201 48
Nonalcoholic fatty liver disease (NAFLD) is the commonest chronic liver disease in high-income countries and is associated with increased morbidity and mortality. Macrophages appear to play an important role in the development and progression of hepatic fibrosis in patients with NAFLD. Accordingly, modulation of macrophage trafficking might represent an attractive therapeutic strategy in this population. Cenicriviroc is an oral inhibitor of the chemokine ligand 2/C-C chemokine receptor 2 pathway ...[more]