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Rapid and Extensive Expansion in the United States of a New Multidrug-resistant Escherichia coli Clonal Group, Sequence Type 1193.

ABSTRACT: We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone-sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates.

SUBMITTER: Tchesnokova VL 

PROVIDER: S-EPMC6321845 | biostudies-other | 2019 Jan

REPOSITORIES: biostudies-other

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Rapid and Extensive Expansion in the United States of a New Multidrug-resistant Escherichia coli Clonal Group, Sequence Type 1193.

Tchesnokova Veronika L VL   Rechkina Elena E   Larson Lydia L   Ferrier Kendra K   Weaver Jamie Lee JL   Schroeder David W DW   She Rosemary R   Butler-Wu Susan M SM   Aguero-Rosenfeld Maria E ME   Zerr Danielle D   Fang Ferric C FC   Ralston James J   Riddell Kim K   Scholes Delia D   Weissman Scott S   Parker Kaveri K   Spellberg Brad B   Johnson James R JR   Sokurenko Evgeni V EV  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20190101 2

We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone-sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates. ...[more]