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Spontaneous pneumococcal peritonitis diagnosed by qPCR.

ABSTRACT: Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with prior or concurrent antimicrobial use. DNA amplification detects very few copies of target DNA under ideal conditions in CSF or pleural effusion and, therefore, can be useful in selected infections. A culture-negative spontaneous pneumococcal peritonitis without preexisting peritoneal disease diagnosed by qPCR is herein described.

SUBMITTER: Jarovsky D

PROVIDER: S-EPMC6327877 | biostudies-other | 2019

REPOSITORIES: biostudies-other

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Spontaneous pneumococcal peritonitis diagnosed by qPCR.

Jarovsky Daniel D Grodzicki Ambrus Thais T Galvão Gurgel Mariana M Jenné Mimica Marcelo M Volpe Arnoni Mariana M Almeida Flávia Jacqueline FJ Palazzi Sáfadi Marco Aurélio MA Naaman Berezin Eitan E

IDCases 20190108

Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with prior or concurrent antimicrobial use. DNA amplification detects very few copies of target DNA under ideal conditions in CSF or pleural effusion and, therefore, can be useful in selected infections. A culture-negative spontaneous pneumococcal pe ...[more]

PMID: 30656139

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