Ontology highlight
ABSTRACT:
SUBMITTER: Adhikari HS
PROVIDER: S-EPMC6332982 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Adhikari Hari Sharan HS Yadav Paras Nath PN
International journal of biomaterials 20181230
Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups can give derivatives of enhanced solubility and remarkable anticancer activity. The general mechanism of such activity is associated with the disturbances in normal functioning of cell cycle, interference to the central dogma of biological system from DNA to RNA to protein or enzymatic synthesis, and the disruption of hormonal path to biosynthesis to inhibit the growth of cancer cells. Both chitosan and its ...[more]