Ontology highlight
ABSTRACT:
SUBMITTER: Purro M
PROVIDER: S-EPMC6345168 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Purro Max M Qiao Jing J Liu Zhi Z Ashcraft Morgan M Xiong May P MP
Chemical communications (Cambridge, England) 20181201 99
The outer membrane of Pseudomonas aeruginosa functions primarily as a permeability barrier and imparts a broad spectrum of intrinsic antibiotic resistance. Herein, we describe the synthesis, characterization, and antimicrobial evaluation of a targeted polymeric micelle that specifically permeabilizes the outer membrane and potentiates antibiotic activity against P. aeruginosa. ...[more]