Ontology highlight
ABSTRACT:
SUBMITTER: Lin A
PROVIDER: S-EPMC6349203 | biostudies-other | 2019 Feb
REPOSITORIES: biostudies-other
Journal of cellular and molecular medicine 20181028 2
The clinical significance of metastasis-associated in colon cancer-1 (MACC1) has been investigated but the relevance of peripheral MACC1 levels was rather limited. Herein, our data revealed that plasma MACC1 levels in 117 colorectal cancer patients (CRC) were dramatically higher than that in normal controls (P < 0.001), and with a strong discrimination power between the two groups (AUC = 0.960, P < 0.001). Moreover, MACC1 is an independent prognostic factor for CRC patients. When clinical parame ...[more]