Impact of Sex Differences and Diabetes on Coronary Atherosclerosis and Ischemic Heart Disease.
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SUBMITTER: Madonna R
PROVIDER: S-EPMC6351940 | biostudies-other | 2019 Jan
REPOSITORIES: biostudies-other
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Impact of Sex Differences and Diabetes on Coronary Atherosclerosis and Ischemic Heart Disease.
Madonna Rosalinda R Balistreri Carmela Rita CR De Rosa Salvatore S Muscoli Saverio S Selvaggio Stefano S Selvaggio Giancarlo G Ferdinandy Péter P De Caterina Raffaele R
Journal of clinical medicine 20190116 1
Cardiovascular diseases (CVD) including coronary artery disease (CAD) and ischemic heart disease (IHD) are the main cause of mortality in industrialized countries. Although it is well known that there is a difference in the risk of these diseases in women and men, current therapy does not consider the sexual dimorphism; i.e., differences in anatomical structures and metabolism of tissues. Here, we discuss how genetic, epigenetic, hormonal, cellular or molecular factors may explain the different ...[more]
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