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"Mendelian Randomization" Approach in Economic Assessment of Health Conditions.


ABSTRACT: The increased prevalence of non-communicable chronic diseases (NCDs) is reflected in the rising economic burden of health conditions. Observational studies conducted in health economics research are detecting associations of NCDs or related risk factors with economic measures like health insurance, economic inequalities, accessibility of jobs, education, annual income, health expenditure, etc. The inferences of such relationships do not prove causation and are limited to associations which are many times influenced by confounding factors and reverse causation. Mendelian randomization (MR) approach is a useful method for exploring causal relations between modifiable risk factors and measures of health economics. The application of MR in economic assessment of health conditions has been started and is producing fruitful results.

SUBMITTER: Gupta V 

PROVIDER: S-EPMC6369183 | biostudies-other | 2019

REPOSITORIES: biostudies-other

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"Mendelian Randomization" Approach in Economic Assessment of Health Conditions.

Gupta Vipin V   Sachdeva Mohinder P MP   Walia Gagandeep Kaur GK  

Frontiers in public health 20190204


The increased prevalence of non-communicable chronic diseases (NCDs) is reflected in the rising economic burden of health conditions. Observational studies conducted in health economics research are detecting associations of NCDs or related risk factors with economic measures like health insurance, economic inequalities, accessibility of jobs, education, annual income, health expenditure, etc. The inferences of such relationships do not prove causation and are limited to associations which are m  ...[more]

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