Ontology highlight
ABSTRACT:
SUBMITTER: Otsuka Y
PROVIDER: S-EPMC6372881 | biostudies-other | 2019 Jul
REPOSITORIES: biostudies-other
Otsuka Yuta Y Egawa Kahori K Kanzaki Noriyuki N Izumo Takayuki T Rogi Tomohiro T Shibata Hiroshi H
Biochemistry and biophysics reports 20190211
Although quercetin has numerous biological benefits, including preventing muscle atrophy due to disuse, no reports have been published to date about the preventive effects and molecular mechanisms underlying drug-induced muscle atrophy. Highly soluble and bioavailable quercetin glycosides (QGs) were used to examine the inhibition of dexamethasone (DEX)-induced muscle atrophy in vivo. Male BALB/cCrSlc mice were treated with or without QGs for 7 days ad libitum, followed by addition of DEX to thei ...[more]