Ontology highlight
ABSTRACT:
SUBMITTER: Zheng X
PROVIDER: S-EPMC6385674 | biostudies-other | 2019 Feb
REPOSITORIES: biostudies-other
Zheng Xujun X Zhu Wencheng W Ni Fan F Ai Hua H Gong Shaolong S Zhou Xiang X Sessler Jonathan L JL Yang Chuluo C
Chemical science 20181227 8
After entering a cell, most small molecule fluorescent probes are dispersed in the cytoplasm before they then accumulate in a specific organelle or subcellular zone. Molecules that can enter two or more organelles with high selectivity are all but unknown. In this work, we report a naphthalimide-based fluorescent probe, <b>NIM-7</b>, that allows lipid droplets and lysosomes to be labelled simultaneously and with high specificity. These subcellular entities can then be visualized readily through ...[more]