Ontology highlight
ABSTRACT:
SUBMITTER: Yao L
PROVIDER: S-EPMC6385897 | biostudies-other | 2019 Feb
REPOSITORIES: biostudies-other
Chemical science 20190110 8
An unprecedented catalytic asymmetric [1,3] O-to-C rearrangement of alkyl 2-allyloxy/benzyloxy-1/3-naphthoates was realized under the catalysis of a chiral π-Cu(ii) complex (1-10 mol%). This dearomatization strategy provides facile access to highly functionalized β-naphthalenone derivatives bearing an all-carbon quaternary stereogenic center in high yield with excellent enantioselectivity. The π-cation interaction between the aromatic substituent of the ligand and the Cu(ii) center was proved by ...[more]