Ontology highlight
ABSTRACT:
SUBMITTER: Riley NM
PROVIDER: S-EPMC6428843 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Riley Nicholas M NM Hebert Alexander S AS Westphall Michael S MS Coon Joshua J JJ
Nature communications 20190321 1
Protein glycosylation is a highly important, yet poorly understood protein post-translational modification. Thousands of possible glycan structures and compositions create potential for tremendous site heterogeneity. A lack of suitable analytical methods for large-scale analyses of intact glycopeptides has limited our abilities both to address the degree of heterogeneity across the glycoproteome and to understand how this contributes biologically to complex systems. Here we show that N-glycoprot ...[more]