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Synchronous non-collision melanoma and basal cell carcinoma arising from chronic lymphedema: a case report and review of literature.


ABSTRACT: Chronic lymphedema (CL) due to failure of lymphatic drainage harbors an immunologically vulnerable environment for the development of various neoplasms. Independently, either melanoma or basal cell carcinoma (BCC) arising from CL has only been reported, but synchronous melanoma and BCC originating from CL is never reported. We report a very rare case of synchronous melanoma and BCC arising from the lymphedematous upper extremity developed secondary to axillary lymphadenectomy for breast cancer. Additionally, a literature review reporting either melanoma or BCC in the lymphedematous area was performed using Medline and PubMed databases.

SUBMITTER: Jaafar S 

PROVIDER: S-EPMC6460899 | biostudies-other | 2019 Apr

REPOSITORIES: biostudies-other

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Synchronous non-collision melanoma and basal cell carcinoma arising from chronic lymphedema: a case report and review of literature.

Jaafar Sahned S   Jestila Tatum T   Waheed Abdul A   Misra Subhasis S   Thakkar Darshan D  

Journal of surgical case reports 20190412 4


Chronic lymphedema (CL) due to failure of lymphatic drainage harbors an immunologically vulnerable environment for the development of various neoplasms. Independently, either melanoma or basal cell carcinoma (BCC) arising from CL has only been reported, but synchronous melanoma and BCC originating from CL is never reported. We report a very rare case of synchronous melanoma and BCC arising from the lymphedematous upper extremity developed secondary to axillary lymphadenectomy for breast cancer.  ...[more]

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