Cationic Albumin Encapsulated DNA Origami for Enhanced Cellular Transfection and Stability.
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ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC6470866 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Publications
Cationic Albumin Encapsulated DNA Origami for Enhanced Cellular Transfection and Stability.
Xu Xuemei X Fang Shiqi S Zhuang Yuan Y Wu Shanshan S Pan Qingling Q Li Longjie L Wang Xiaohui X Sun Xueqing X Liu Bifeng B Wu Yuzhou Y
Materials (Basel, Switzerland) 20190321 6
DNA nanostructures, owing to their controllable and adaptable nature, have been considered as highly attractive nanoplatforms for biomedical applications in recent years. However, their use in the biological environment has been restricted by low cellular transfection efficiency in mammalian cells, weak stability under physiological conditions, and endonuclease degradation. Herein, we demonstrate an effective approach to facilitate fast transfection of DNA nanostructures and enhance their stabil ...[more]
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