Ontology highlight
ABSTRACT:
SUBMITTER: Chiboub O
PROVIDER: S-EPMC6471066 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Chiboub Olfa O Sifaoui Ines I Lorenzo-Morales Jacob J Abderrabba Manef M Mejri Mondher M Fernández José Javier JJ Piñero José E JE Díaz-Marrero Ana R AR
Marine drugs 20190325 3
Bioassay-guided fractionation of the antikinetoplastid extract of the brown alga <i>Dictyota spiralis</i> has led to the isolation of spiralyde A (<b>1</b>), a new dolabellane aldehyde, along with other five known related diterpenes (<b>2</b>⁻<b>6</b>). Their structures were determined by HRESIMS, 1D and 2D NMR spectroscopy, and comparison with data reported in the literature. The antiparasitic activity of all compounds was evaluated. Spiralyde A (<b>1</b>) and the known compound 3,4-epoxy-7,18- ...[more]