Ontology highlight
ABSTRACT:
SUBMITTER: Itaba N
PROVIDER: S-EPMC6497888 | biostudies-other | 2019 May
REPOSITORIES: biostudies-other
Itaba Noriko N Kono Yohei Y Watanabe Kaori K Yokobata Tsuyoshi T Oka Hiroyuki H Osaki Mitsuhiko M Kakuta Hiroki H Morimoto Minoru M Shiota Goshi G
Scientific reports 20190502 1
Chronic hepatitis viral infection, alcoholic intoxication, and obesity cause liver fibrosis, which progresses to decompensated liver cirrhosis, a disease for which medical demands cannot be met. Since there are currently no approved anti-fibrotic therapies for established liver fibrosis, the development of novel modalities is required to improve patient prognosis. In this study, we clarified the anti-fibrotic effects of cell sheets produced from human bone marrow-derived mesenchymal stem cells ( ...[more]