Ontology highlight
ABSTRACT:
SUBMITTER: Pizzinga M
PROVIDER: S-EPMC6504908 | biostudies-other | 2019 May
REPOSITORIES: biostudies-other
The Journal of cell biology 20190315 5
mRNA localization serves key functions in localized protein production, making it critical that the translation machinery itself is present at these locations. Here we show that translation factor mRNAs are localized to distinct granules within yeast cells. In contrast to many messenger RNP granules, such as processing bodies and stress granules, which contain translationally repressed mRNAs, these granules harbor translated mRNAs under active growth conditions. The granules require Pab1p for th ...[more]