Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside.
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SUBMITTER: Li S
PROVIDER: S-EPMC6530230 | biostudies-other | 2019
REPOSITORIES: biostudies-other
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Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside.
Li Sicheng S Hu Qiongyuan Q Huang Jinjian J Wu Xiuwen X Ren Jianan J Ren Jianan J
Oxidative medicine and cellular longevity 20190508
Sepsis is one of the most serious health hazards. Current research suggests that the pathogenesis of sepsis is mediated by both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Mitochondria are among the most important organelles in cells and determine their life and death. A variety of mitochondria-derived DAMPs (mtDAMPs) are similar to bacteria because mitochondria are derived from bacteria according to the mitochondrial endosymbiotic theory. The ...[more]
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