Ontology highlight
ABSTRACT:
SUBMITTER: Feng H
PROVIDER: S-EPMC6556903 | biostudies-other | 2019 Mar
REPOSITORIES: biostudies-other
Feng Hao H Jin Peng P Wu Hao H
Briefings in bioinformatics 20190301 2
Disease diagnosis using cell-free DNA (cfDNA) has been an active research field recently. Most existing approaches perform diagnosis based on the detection of sequence variants on cfDNA; thus, their applications are limited to diseases associated with high mutation rate such as cancer. Recent developments start to exploit the epigenetic information on cfDNA, which could have substantially wider applications. In this work, we provide thorough reviews and discussions on the statistical method deve ...[more]